Buprenorphine FDA Link Generic

A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.

Also Known As:

Subutex; Buprenex; 6029-M; Buprenorphine Hydrochloride; Buprex; Prefin; RX-6029-M; Temgesic; Temgésic; 6029 M; 6029M; Hydrochloride, Buprenorphine; RX 6029 M; RX6029M; 6,14-Ethenomorphinan-7-methanol, 17- (cyclopropylmethyl)- alpha- (1,1- dimethylethyl)- 4,5- epoxy- 18,19- dihydro- 3- hydroxy- 6- methoxy- alpha- methyl- , (5alpha,7alpha(S))-

Pharmalogical Action Categories:

Analgesics, Opioid
Narcotic Antagonists
Narcotics

Heterocyclic Compounds: 207
- Alkaloids: 5592
  - Opiate Alkaloids: 5977
    - Morphinans: 35
      - Buprenorphine: 4375
- Bridged-Ring Heterocyclic Compounds
  - Morphinans: 35
    - Buprenorphine: 4375
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - Morphinans: 35
      - Buprenorphine: 4375
Polycyclic Compounds: 7
- Polycyclic Aromatic Hydrocarbons: 2081
  - Phenanthrenes: 29
    - Morphinans: 35
      - Buprenorphine: 4375

Karolina Bogdanowicz Selected Research

Karolina Bogdanowicz Research Topics

Disease

Drug/Important Bio-Agent (IBA)